Obesity in childhood can increase the incidence of type 2 diabetes mellitus (DM).It is also at risk of becoming obese in adulthood.May cause glucose metabolism disorders and degenerative diseases.Besides, obesity in children aged 6-7 years can also reduce intelligence level due to decreased activity and creativity of children, and tend to be lazy d
The present paper describes experiments and research outcomes concerning the construction of cement concrete pavements in South Kazakhstan, taking into account significant climate changes.The study has identified potential problems in the construction of cement concrete pavements in the region, where there was no experience of their construction un
A UNESCO project, Support for the Preparation for the World Heritage Serial Nomination of the Silk Roads in South Asia, afforded the opportunity to research evidence for Silk Roads exchange in South Asia.The first part of the paper explores the challenges of archaeology in the Kingdom of Bhutan, located on the southern slopes of the eastern Rangeho
Abstract Orderly development of neuroendocrine and nervous system of mammals requires INSM1, a key regulator for cell differentiation.Ectopic expression of INSM1 is closely correlated with human neuroendocrine tumorigenesis, which makes INSM1 Cutting Board Brushes a reliable diagnostic biomarker and potential therapeutic target.To date, INSM1 is kn
Abstract Background Translocations are hallmarks of non-Hodgkin lymphoma (NHL) genomes.Because lymphoid cell development processes require the creation and repair of double stranded breaks, it is not surprising that disruption of this type of DNA repair can cause cancer.The members of the MRE11-RAD50-NBS1 (MRN) complex and BLM have central roles in